Stem cells for weight loss are a reality!

Today we will talk about the treatment of metabolic syndrome with stem cells in Kiev 

Kiev is a city of European level and European opportunities. We all want to look presentable, as well as to improve our health and physical capabilities. Treatment of metabolic syndrome with stem cell preparations in Kiev is one of the best opportunities to achieve results;

The combination of standard methods of obesity treatment with the introduction of cellular preparations (products derived from placenta and stem cells) makes it possible to lose excess weight effectively and without unnecessary effort. This helps to avoid the appearance of associated diseases and normalize metabolic processes.

Contents:Contents:

• Stem cells and metabolic syndrome
• What is the outcome of stem cell treatment for metabolic syndrome
• Who is suitable for stem cell treatment
• How cell therapy works
• Benefits of stem cells
• How to treat metabolic syndrome
• How the cell therapy procedure works
• Anesthesia in stem cell treatment
• Stages of Cell Therapy
• Will your expectations of therapy be met
• Frequent questions about treating metabolic syndrome
• Advanced treatments to improve appearance

What is obesity?

Obesity (metabolic syndrome) is an increase in the amount of fat that is deposited in the waist area (another definition is visceral fat), decreased tissue sensitivity to insulin and increased insulin content in the body. These factors disrupt metabolism, primarily carbohydrate and lipid metabolism, and cause hypertension (increased blood pressure).

Risk Factors:

• Overweight or obese, with fat deposits mainly around the waist (critical waist volume for men from 102 cm, women from 88 cm);
• elevated blood glucose levels;
• increased blood pressure;
• elevated cholesterol and triglyceride levels;
• High-density lipoprotein (HDL) levels are too low.

The role of stem cells in the treatment of metabolic syndrome

Doctors use two types of cells for the therapy of metabolic syndrome.

Patient’s own cells (autologous)

In this case, cells are used that are taken from the patient’s body. After the biomaterial is collected, a team of biotechnologists produces a therapeutic dose of stem cells. Then, according to the developed technologies, the necessary number of cells is grown. The material is tested, and then a cellular product for therapy is created from it. Usually the production period of the product is no more than 21 days.

Donor cells (allogeneic)

Taking into account the doctor’s prescription, the biotechnologist selects ready-made donor cell material from the cryobank. All samples in the cryobank are tested in advance and have been checked for safety. In this case, the introduction of stem cells into the recipient’s body can be carried out immediately after diagnosis and appropriate preparation.

What stem cell treatment for metabolic syndrome provides

You have the opportunity to determine for yourself whether your body has metabolic syndrome by using the table below. If your values are identical to 3 or more of the values in this table, you have metabolic syndrome.

Health Problem.	Indicator
Large Waist Circumference (waist circumference)	Men – 102 cm and overWomen – 88 cm and over
High triglyceride content	150 milligrams per deciliter or higher; taking medications to lower triglycerides
Low High Density Lipoprotein Cholesterol(HDL Cholesterol)	Less than 40 mg/dL for menLess than 50 mg/dL for women
High blood pressure	130/80 or higher; taking medications to lower blood pressure
High fasting blood glucose	100 mg/dL or higher; taking blood glucose-lowering medications

The procedure of stem cell injection in the presence of metabolic syndrome can solve many other issues in addition to improving the appearance:

• Normalization of the ratio of ghrelin (another name: “hunger hormone”) and leptin (“satiety hormone”);
• normalization of blood glucose content;
• An increase in “good cholesterol” (HDL) and a decrease in “bad cholesterol” (LDL);
• lowering the amount of triglycerides in the blood;
• normalization and stabilization of blood pressure;
• Reducing the risk of stroke, heart attack and diabetes mellitus;
• Improved sexual function and attraction in both sexes;
• increased activity, concentration, performance and quality of life in general.

To solve the problem of weight loss with the help of stem cells, mainly intravenous cell therapy is performed. Depending on the main localization of the disease, the doctor may additionally prescribe local administration of the cell product.

Who will benefit from stem cell treatment for metabolic syndrome

This procedure is indicated for everyone who wants to get rid of excess weight, improve health and bring it to a stable state. However, there are contraindications. For example, stem cells cannot be prescribed to patients with the acute phase of chronic and infectious diseases. Stem cell treatment is not administered to pregnant and lactating women.

Other contraindications for cell therapy:

1. Blood clotting disorders, hemophilia.
2. Presence of chronic diseases.
3. Precancerous conditions.
4. Malignant tumor history within the last 5 years.
5. A decrease in the level of platelets in the blood.
6. Blood diseases that can cause damage to bone marrow stem cells.
7. Parasitic cysts.
8. Prolonged use of antibiotics or hormonal drugs with possible damage to bone marrow cells.
9. Active form of AIDS, tuberculosis, viral hepatitis.
10. Infectious agents of hepatitis B or C, T.pallidum, HIV, Mycoplasma spp., Herpes virus 6, VEB, CMV in blood tests.
11. Age (at least 18 years old).

How does stem cell therapy for metabolic syndrome work?

This therapy provides two options: doctors collect and grow the patient’s own cells or use donor cells. The second option is suitable for shortening the treatment period;

Modern high-tech equipment – cryochamber – allows storing biomaterials (including stem cells) for an unlimited amount of time.

As a result of therapy, we can see an increase in the quality of the pancreas, liver, intestines and other organs and systems of the body, improving metabolism, normalization of blood glucose and beneficial effects on the whole body.

Each cell product has its own passport. Work with stem cells is carried out exclusively according to EU safety protocols.

The benefits of cell therapy to solve your specific problem

At the Kulazer Clinic, every patient receives:

• the possibility of using one’s own biomaterial, which significantly reduces the likelihood of an immune response after administration of the stem cell preparation;
• Consultation with a qualified specialist, individual selection of procedures and treatment plan, taking into account all nuances.

In addition to metabolic syndrome, stem cells have been successfully used to treat more than 300 diseases. Among them are the most common: diabetes, multiple sclerosis, cartilage regeneration, trauma, Alzheimer’s disease, Parkinson’s disease, stroke and general rejuvenation of the body.

When and how often metabolic syndrome can be treated with stem cells

The number of procedures and the amount of injected material will be selected by a specialist at an individual consultation, taking into account the patient’s anamnesis. Usually 1-2 procedures are prescribed, the course can be repeated after 6 months. Results in the form of improvement in the general condition of the body can be observed in two weeks after treatment. But a prerequisite for this – compliance with all recommendations of the doctor!

The treatment program itself lasts up to 7 days on average, but the duration also depends on the type of cells used in the procedures. In case autologous stem cells are used, more time is needed. It takes 3 to 4 weeks to grow them to the desired volume. Sometimes the doctor may recommend repeating the course in six months to consolidate the effect.

Besides weight loss, there are other benefits visible to the naked eye. The use of stem cells as a means of rejuvenation (topically and/or intravenously) has the effect of smoothing out fine lines and wrinkles. This is due to the stimulation by stem cells of the synthesis of elastic fibers, increased blood circulation in the dermis and metabolic processes in general.

The possibility of cell therapy after Botox and contouring should be agreed with the doctor individually. This precautionary measure takes into account the need to stop taking certain medications for a certain period before cell injection.

What is the procedure for stem cell treatment of metabolic syndrome?

The treatment is carried out only by qualified subject matter experts with mandatory compliance with EU safety protocols. In addition to the specialized specialist, biotechnologists are involved in the process. Their task  is to grow the required volume of cells in a specially equipped high-tech biolaboratory. Biotechnologists are also responsible for the correct storage of the cell product in the cryochamber.

Stem cells are most commonly taken from umbilical cord blood. Their content in cord blood is 10-12 times higher than in bone marrow. Cord blood is currently the easiest and safest source of stem cells. In cases where it is not possible to obtain a product from cord blood, adipose tissue is taken. This method is also common, as the patient’s body is less traumatized when the biomaterial is taken.

Benefits of mesenchymal stem cells isolated from adipose tissue:

1. Convenient and efficient acquisition of material compared to peripheral blood or red bone marrow.
2. Большее количество полученных стволовых клеток чем из других тканей.
3. The cells have a high proliferative potential, which means that they can be easily multiplied in the laboratory to the number needed for therapy.
4. Such cells secrete cytokines, hyaluronic acid, collagen, elastin, glycosaminoglycans. These substances promote tissue regeneration (i.e. tissue repair).

There are two options for harvesting adipose tissue for cell preparation.

Lipoaspiration (liposuction)

During this procedure, in consultation with the patient, an area with excess fat deposits is selected, from which further cell harvesting is performed. The most common sites are:

• fatty tissue in the abdominal area;
• fat on the flanks or thighs.

Lipoaspiration is usually performed by a surgeon. He puts the patient under local anesthesia in the operating room. General anesthesia can be provided at the patient’s request.

Punch biopsy.

It is a minimally traumatic method of cell sampling using a special instrument that allows you to take material from deeper tissues and organs. Punch biopsy does not require special preparation. Before it should exclude the patient’s application of various ointments or creams to the skin in the area of the procedure. Biopsy is performed under local anesthesia in a manipulation room with a high level of sterility.

The prepared cell preparation is injected intravenously and, in some cases, topically. The whole procedure will take up to 2 hours, together with anesthesia.

Anesthesia in cell therapy

There is often a question about the use of anesthesia in the process of stem cell treatment. The procedure of cellular material collection itself takes place in outpatient conditions, and the use of general anesthesia is rarely practiced. After pretreatment of the skin with antiseptic and local anesthesia, the doctor performs a tissue biopsy. But at the patient’s request and in agreement with the doctor, general anesthesia is also possible.

The duration of anesthetic application and waiting for the effect of anesthesia depends on the type of drug applied, the effect can occur after 2-3 minutes and last up to two hours. Both the drug and the dose of anesthesia will be selected for the patient individually. Accordingly, the waiting time for the effect and duration of action may vary.

Stages of cell therapy

The mesenchymal stem cell treatment protocol includes a preparatory course, obtaining cellular material and direct injection of the biomaterial with follow-up of the patient. A second procedure may be recommended after 6 months.

Stem cell treatment for metabolic syndrome is divided into the following steps:

1. Consultation with a subspecialist to review the situation and develop an individualized treatment plan.
2. Laboratory tests: urinalysis, blood count, blood chemistry, blood group and Rh, coagulogram.
3. Biomaterial collection (in case autologous cells of the patient are used).
4. Cultivation (cultivation) in a biolaboratory.
5. Infection screening of cellular material (safety testing).
6. Introduction of the prepared material into the patient’s body.
7. Adherence to a special regimen and doctor’s recommendations (this may be limitation of physical activity, exclusion of toxic and highly digestible foods from the diet, avoidance of too high and too low temperatures);
8. If necessary, a second consultation with a specialist.

A standard treatment program lasts up to 7 days. Occasionally, a repeat course of treatment may be recommended (not earlier than after 6 months). Hospitalization is not necessary if the patient has no motor impairment. After the initial consultation, the doctor will make a calculation of the number of courses required and their cost. The duration of treatment depends on the stage of the disease and the presence of possible concomitant pathologies.

Will your expectations from cell therapy 

Significant improvement in the condition and progress in the treatment of concomitant diseases (such as high blood pressure, elevated blood glucose levels) is noted within a few weeks after the procedure. According to the data obtained after treatment, after 2-3 months the main symptoms of the disease are reduced. Within a year, the activity of the immune system is restored;

The duration of the effect depends on many factors (among others, age, presence of comorbidities), as well as on the accuracy of compliance with the doctor’s recommendations. Compliance with a special regimen may include limited physical activity, exclusion of toxic foods from the diet, limiting exposure to too high and low temperatures (ban on visiting the sauna for a certain period of time). There is no  need for a stay in the hospital after the procedure or observing complete rest. It is possible to continue to live in the standard mode, taking into account the restrictions recommended by the doctor.

Frequently Asked Questions

Take advantage of the opportunity to get in the center of Kiev on Pechersk in the licensed Coolaser Clinic stem cell treatment at the most loyal prices!

Procedures that complement cellular therapy

Patients most often continue to correct their appearance after stem cell treatment with these methods:

1. CMAS facelift for skin rejuvenation and tightening.
2. Cellulite removal with the Venus Versa machine.
3. Removal of papillomas and other skin neoplasms.

Sources:Sources:

Sloan-Kettering Institute, Cancer Center, USA

Medical Center Medicare4U Ltd, United Kingdom

Stem Cell Center iVF Riga, Latvia

Clinica Assuta, Israel